Mesemoa started their career in 2012 as a cover dance group called "Morning Musumen (モーニングむすめん。or just simply むすめん。 for short) - they chose this name because most of their covers were from longtime girl group Morning Musume. Their videos were mostly uploaded their videos on niconico until they began uploading on YouTube.
At the beginning of 2017, they officially changed their name to "Mesemoa". All their dance performances are choreographed by their graduated member K'suke.
The group has one subunit: Traffic Light. It includes members Shirofuku, Aoi, and Kimagure Prince who all go by their birth name and were a unit when Mesemoa was still Musumen.
In August of 2017, Mesemoa teased their new single「Muddy Water」. The teasers show the members dancing in the pouring rain. The teasers and video was labeled as their 1st single - meaning their first official single as Mesemoa. The video dropped August 5, 2017; the single to be released August 26 with 4 different CDs.